People who achieve weight loss of 10 per cent or more in the
first five years after being diagnosed with type 2 diabetes have
the greatest chance of their diabetes going into remission,
according to a study led by the University of Cambridge.
The findings suggest that it is possible to achieve remission
without intensive lifestyle interventions or extreme calorie
To find out whether less intensive interventions work, a team of
researchers studied data from the ADDITION-Cambridge trial, a
prospective cohort study of 867 people with newly diagnosed
diabetes aged 40 and 69 years recruited from general practices in
the eastern region.
The researchers found that 257 participants (30 per cent) were
in remission after five years.
People who achieved weight loss of 10 per cent or more within
the first five years after diagnosis were more than twice as likely
to go into remission compared to people who maintained the same
"We've known for some time now that it's possible to send
diabetes into remission using fairly drastic measures such as
intensive weight loss programmes and extreme calorie restriction,"
said Dr Hajira Dambha-Miller.
"These interventions can be very challenging to individuals and
difficult to achieve. But, our results suggest that it may be
possible to get rid of [type 2] diabetes, for at least five years,
with a more modest weight loss of 10 per cent. This will be more
motivating and hence more achievable for many people."
Click here to read the
original study published in Diabetic Medicine.